scholarly journals Lymphocyte transformation changes during the clinical course of Hodgkin's disease

Cancer ◽  
1970 ◽  
Vol 25 (4) ◽  
pp. 843-850 ◽  
Author(s):  
S. M. Jackson ◽  
J. V. Garrett ◽  
A. W. Craig
Keyword(s):  
Hodgkin's Disease ◽  
Clinical Course ◽  
Hodgkin’S Disease ◽  
Lymphocyte Transformation

scholarly journals Phytohemagglutinin-induced Lymphocyte Transformation: The Relationship to Prognosis of Hodgkin’s Disease

Blood ◽  
1972 ◽  
Vol 39 (5) ◽  
pp. 595-601 ◽  
Author(s):  
Michael P. Corder ◽  
Robert C. Young ◽  
Robert S. Brown ◽  
Vincent T. DeVita
Keyword(s):  
Hodgkin's Disease ◽  
Clinical Course ◽  
Hodgkin’S Disease ◽  
Lymphocyte Transformation ◽  
Nodular Sclerosis ◽  
Peripheral Leukocyte ◽  
General Index ◽  
Histologic Pattern ◽  
The Relationship ◽  
Immunologic Status

Abstract Forty-three untreated patients with Hodgkin’s disease were evaluated between 1965 and 1967 with PHA-stimulated peripheral leukocyte cultures. No correlation was found between PHA-induced lymphocyte transformation at the time of diagnosis and the clinical course of the patient’s Hodgkin’s disease. There is also no correlation between lymphocyte transformation and the histologic pattern of nodular sclerosis. Although PHA-induced lymphocyte transformation appears to be a general index of immunologic status, it has not proven of value as a prognostic sign in Hodgkin’s disease.

Clinical Course and Outcome of Patients with Hodgkin's Disease who Progress after Autologous Transplantation

1995 ◽  
Vol 20 (1-2) ◽  
pp. 59-65 ◽  
Author(s):  
Mary Varterasian ◽  
Voravit Ratanatharathorn ◽  
Joseph P. Uberti ◽  
Chatchada Karanes ◽  
Esteban Abella ◽  
...  
Keyword(s):  
Hodgkin's Disease ◽  
Clinical Course ◽  
Hodgkin’S Disease ◽  
Autologous Transplantation

scholarly journals Correlation between abnormal baseline liver tests and long-term clinical course in Hodgkin's disease

Cancer ◽  
1974 ◽  
Vol 33 (4) ◽  
pp. 1123-1126 ◽  
Author(s):  
Ralph E. Johnson ◽  
Louis B. Thomas ◽  
Sandra K. Johnson ◽  
Gerald S. Johnston
Keyword(s):  
Hodgkin's Disease ◽  
Clinical Course ◽  
Hodgkin’S Disease ◽  
Liver Tests

Antibodies to human herpes virus-6 and clinical course in patients with Hodgkin's disease

1992 ◽  
Vol 51 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Paul H. Levine ◽  
Peter Ebbesen ◽  
Dharam V. Ablashi ◽  
W. Carl Saxinger ◽  
Axel Nordentoft ◽  
...  
Keyword(s):  
Hodgkin's Disease ◽  
Herpes Virus ◽  
Clinical Course ◽  
Hodgkin’S Disease ◽  
Human Herpes ◽  
Human Herpes Virus ◽  
Human Herpes Virus 6 ◽  
Herpès Virus

Recurrence of Hodgkin's Disease after a 28-Year Disease-Free Interval. A Case Report

1989 ◽  
Vol 75 (6) ◽  
pp. 637-639
Author(s):  
Lia Ginaldi ◽  
Lanfranco Venturoni ◽  
Girolamo Cretara ◽  
Dennis Quaglino
Keyword(s):  
Hodgkin's Disease ◽  
Systemic Chemotherapy ◽  
Clinical Course ◽  
Hodgkin’S Disease ◽  
Clinical Stage ◽  
Histologic Subtype ◽  
Disease Free Interval ◽  
Free Interval ◽  
Disease Free ◽  
Nodular Sclerosing

The authors describe a case of nodular-sclerosing Hodgkin's disease, originally observed in clinical stage III B and treated by systemic chemotherapy, with relapse after a 28-year disease-free interval. As far as we know, the length of remission in this case is second only to that of a case recently described by Hung and coworkers. Therefore, although according to data in the literature relapse after a very long disease-free interval is more frequently observed in patients with stage I A and II A disease, it may occur also in cases with symptomatic, widespread disease. This phenomenon, while reflecting the complexity of relations between the different factors (histologic subtype, clinical stage, host vs tumor defenses, therapy, etc.) that variously affect the clinical course and outcome, underlines the need for cautiousness when assessing the ultimate prognosis of individual cases of Hodgkin's disease.

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